Thursday, January 1, 2009

Sickbutrin


Recently, a columnist on Huffington Post investigated the reasons the Wall Street Journal was inimical to the proposed integrative health care programs for improving health care delivery in the United States and including more people. Drs. Andrew Weill and Deepak Chopra are avid supporters, and they are both well-respected physicians nationally. The author concluded it was because Big Pharm would lose revenues; they make nothing if a patient is told to use some cheap witch hazel on an insect bite rather than buying an expensive cortisone cream.

In that vein, I offer a column I wrote in 2006 in dismay over a then-current TV advertisement that would have had me howling with laughter had it not been so frightening.

Here then, I offer you

SICKBUTRIN

Like a lot of other Americans who don’t believe God is spelled D-o-c-t-o-r, I’m a little tired of seeing TV ads for prescription medications one can ask one’s doctor about taking. But this week, the ads for Wellbutrin tm pushed me over the edge; I am now in full-tilt revolt against the pharmaceutical manufacturers.


Here’s the gist of the TV spot: Take Wellbutrin tm for depression because there’s a low incidence of sexual side effects. If you take it, you may, however, experience one or more of these side effects:

  • Seizure
  • …….

OK. Stop right there. Why would anyone want to risk a seizure to get over a little bout of feeling blue, or even a large bout of feeling blue? I mean, crying in public beats the pants off falling down on the floor unconscious, getting carted off to the emergency room at some outrageous cost, and having one’s driving privilege revoked. Because in many states, if you show up at a hospital and get diagnosed with a seizure, you don’t have to worry about informing the Dept. of Motor Vehicles about it; the hospital will. You can then forget about getting behind the wheel until six months have passed without another incident. By then, of course, you will either have lost your job (talk about depressing!) because you can’t get there, or annoyed friends and family with constant requests for rides here, there and everywhere until you don’t have many of those either (talk about depressing!), or maybe you’ve just killed yourself because you couldn’t deal with the depression the side effects of this feel-good capsule produced.

Well, you might think, but how many folks would suffer that side effect? Don’t know. The Web site I viewed didn’t have those numbers and, frankly, I didn’t feel like hunting for them. The fact that that side effect is the one now mentioned FIRST in their TV spot said it all for me.

But wait, there’s more. In case the thought of a seizure doesn’t put you off, maybe one of these unpleasant possibilities will:

  • Dry mouth
  • Headache
  • Increased sweating (fat girls beware!)
  • Nausea/vomiting (how quaint)
  • Constipation (I didn’t say a word)
  • Anxiety
  • Fatigue
  • Blurred vision (another one that’s really fine for driving skills)

But wait, there’s more. The Web site also advises reporting promptly:

  • Unusual weight loss or gain
  • Palpitations
  • Agitation
  • Trouble sleeping

But wait, there’s more. These are labeled “Unlikely, but report promptly:”

  • Tremor
  • Dizziness
  • Fainting
  • Mood changes
  • Slowed movements
  • Difficulty urinating
  • Decreased sex drive (AHA!)
  • Drowsiness

And then there is the “Very unlikely” category, which includes:

  • Seizures
  • Mental problems
  • Fever
  • Muscle aches
  • Yellowing of the eyes or skin

Reading on a bit in the disclaimer on the Web site www.Wellbutrinsite.com, one might get the idea that this drug is for people on heavy-duty mood altering medication. It says: “Suddenly stopping certain tranquilizers (e.g., diazepam, chlordiazepoxide) is not recommended because doing so may increase the risk of having seizures.”

Yipes. So maybe it’s fine, then, about all those other side effects. But hey, if a patient is already juiced out of their gourd on deadly chemicals in tiny doses packed in pastel pills, why would that person be worrying about the incidence of sexual side effects anyway? From the disclaimers on the Web site, it would appear that most of the people who would seek or use Wellbutrin tm are, well, outside the mainstream of human interaction already. In short, if you’re drugged out of your senses, then it would seem the only sex you might be betting would be the sort which, when a result of Rohypnol, is called Date Rape. In short, if you’re so fuzzy-headed you don’t know which end is up, someone’s probably taking advantage of that situation, and you don’t know much about it anyway, so again, who cares?

About that point in the research, I thought it would be nice to have the manufacturer’s name. But it is not to be found on the Web site I was viewing, the one through which you can place really big orders for the stuff. Still, looking for it was fun. That exercise revealed that the non-timed-release version of the drug, in its development and post-marketing phase (so apparently it was released for sale while still being developed? I thought the FDA was involved here….), offered lots of other side effects. Lots. I mean like a dozen or more for each of the systems in the human body, from brain to butt. These I really liked:

  • cystitis
  • abnormal ejaculation (AHA! again)
  • urinary incontinence (lovely!)
  • menopause (Why bother waiting for those hot flashes! Have them now!)
  • penis disorder
  • vaginitis

Those were not all of the genitourinary system disorders, just my favorites.

Some people will say I’m over-reacting or using scare tactics, or that I am politically incorrectly assaulting the hopes of the poor, downtrodden depressed population.

I say: If you think courting any one of the few possible side effects I have mentioned might be fun, why not do this? Just go find someone who has epilepsy and ask if he or she would recommend taking the chance of getting it. Ask someone with Parkinson’s disease if having tremors is a treat. Do you enjoy gaining weight? Swallowing Milk of Magnesia? Do you want your penis, for crying out loud, to be disordered? Or perhaps the sweats and cravings and sometimes hair loss and other menopausal excitements excite you.

I have been depressed. Everyone has been depressed. (Well, maybe not Dr. Phil or Dr. Wayne Dyer. But everyone else.) I may even, at times, have been clinically depressed. My mother was depressed forever. I have relatives who had been diagnosed with severe mood disorders. And I’m a freelance writer; I’m always living on the edge, always waiting for a check or screaming for it, and sometimes tucking my tail between my legs and asking friends or family for a bailout. Talk about depressed! I have found a good book, a glass of wine, a walk down a country lane, or even planning something pleasant helps. I may still feel depressed, but less so than otherwise, and a lot less so than risking any one of the disasters described on that Web site.

Even on my worst dark, lonely, depressed days—when my rent is due, the car needs work, my dog is out of food, I’ve had pasta for one week straight and my publishers still haven’t sent the check—you couldn’t pay me all the royalties of Gone with the Wind, Catcher in the Rye and the Harry Potter books combined to get me to swallow one single sample of Wellbutrin tm.

By the way, the manufacturer of the stuff is GlaxoSmithKline.